Drug Target Interaction
Chapter Name : Chemistry In Everyday Life |
Sub Topic Code : 102_12_16_02_02 |
Topic Name : Drug Target Interaction |
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Sub Topic Name : Receptors As Drug Targets |
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Introduction
The inventive process of finding new medications based on the knowledge of a biological target.
Pre-Requisites:
Drug design
Activity:
Drugs.
Real Life Question:
What are Biological target?
Key Words / FlashCards
| Key Words | Definitions (pref. in our own words) |
|---|---|
| Biological target | A biological target is a biopolymer such as a protein or nucleic acid whose activity can be modified by an external stimulus. |
Learning aids / Gadgets
| Gadgets | How it can be used |
|---|---|
| Enzyme | Enzymes are large biological molecules responsible for the thousands of chemical interconversion that sustain life. And by studying them. |
Real life uses :
Medication.
Places to visit :
Pharmacy.
Practical examples around us
| Examples | Explainations |
|---|---|
| ligand | Ligand (from the Latin ligandum, binding) is a substance (usually a small molecule), that forms a complex with a biomolecule to serve a biological purpose. In a narrower sense, it is a signal triggering molecule, binding to a site on a target protein. |
What you learn in Theory:
A biological target is a biopolymer such as a protein or nucleic acid whose activity can be modified by an external stimulus. Drug design, sometimes referred to as rational drug design or more simply rational design, is the inventive process of finding new medications based on the knowledge of a biological target.
What you learn in Practice:
The implication is that a molecule is "hit" by a signal and its behavior is thereby changed. Biological targets are most commonly proteins such as enzymes, ion channels, and receptors.